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个人简介Personal Profile
李威博士，国家高层次青年人才引进计划加入华中科技大学。2008年和2011年在西安交通大学材料科学与工程学院先后获得学士和硕士学位；2015年博士毕业于德国埃尔朗根-纽伦堡大学生物材料研究所；2019年和2020年在芬兰赫尔辛基大学药学院先后获得Principal Investigator和Docent (Adjunct Professor)头衔，随后被遴选为赫尔辛基生命科学研究所HiLIFE Fellow。
主要研究领域为纳米药物、药物递送和生物材料，以微流控为技术平台，聚焦药物在微纳米载体中的高效包载与可控释放。以通讯或第一作者身份在Nat Commun、Adv Mater、Adv Funct Mater和Mater Horiz等期刊发表学术论文20余篇；作为项目负责人曾主持芬兰主要的公立、私立和药企基金会研究项目十余项。曾担任北欧药学联合会年会的分会场主席；获得赫尔辛基大学药学院优秀青年研究员、芬兰药学会年度最佳论文等荣誉奖项；受邀担任六十余种国际期刊和会议摘要的审稿人、Bioact Mater编委、欧盟多国基金函评或会评专家。
团队（含国外合作/联合培养）现有教师2名、博士后4名、博士生5名、硕士生1名、本科生1名、科研助理1名。因发展需要，课题组长期招收研究生、博士后，诚挚邀请具有生物医学工程/药学/材料/化学等教育背景，药物递送/纳米药物/药物制剂/生物材料等研究背景，热爱科学研究的同学加入，待遇从优，共同发展。此外，欢迎本科生来课题组开展研究工作。有意者请将个人简历和学术证明材料发至liwei2023@hust.edu.cn。
代表性论文列表：
W. Li†, J. Chen†, S. Zhao, T. Huang, C. Trujillo, G. Molinaro, Z. Zhou, T. Jiang, W. Liu, L. Li, Y. Bai, P. Quan, Y. Ding, J. Hirvonen, G. Yin*, H.A. Santos*, J. Fan*, D. Liu*, High drug-loaded microspheres enabled by controlled in-droplet precipitation promote functional recovery after spinal cord injury. Nature Communications. 2022;13:1262.
S. Wang, S. Wannasarit, P. Figueiredo, G. Molinaro, Y. Ding, A. Correia, L. Casettari, R. Wiwattanapatapee, J. Hirvonen, D. Liu, W. Li* (co-corresponding author), H.A. Santos, Intracellular delivery of budesonide and polydopamine co-loaded in endosomolytic poly(butyl methacrylate-co-methacrylic acid) grafted acetalated dextran for macrophage phenotype switch from M1 to M2, Advanced Therapeutics. 2021:2000058.
S. Wang, S. Wannasarit, P. Figueiredo, J. Li, A. Correia, B. Xia, R. Wiwattanapatapee, J. Hirvonen, D. Liu, W. Li* (co-corresponding author), H.A. Santos*. Superfast and controllable microfluidic inking of anti-inflammatory melanin-like nanoparticles inspired by Cephalopod. Materials Horizons. 2020;7:1573-80.
S. Wannasarit, S. Wang*, P. Figueiredo, C. Trujillo, F. Eburnea, L. Simón-Gracia, A. Correia, Y. Ding, T. Teesalu, D. Liu, R. Wiwattanapatapee, H.A. Santos*, W. Li* (corresponding author & last author), A virus-mimicking pH-responsive acetalated dextran-based membrane-active polymeric nanoparticle for intracellular delivery of antitumor therapeutics, Advanced Functional Materials. 2019;29:1905352.
W. Li†, Y. Li†, Z. Liu†, N. Kerdsakundee, M. Zhang, F. Zhang, X. Liu, T. Bauleth-Ramos, W. Lian, E. Mäkilä, M. Kemell, Y. Ding, B. Sarmento, R. Wiwattanapatapee, J. Salonen, H. Zhang, J.T. Hirvonen, D. Liu*, X. Deng*, H.A. Santos*. Hierarchical structured and programmed vehicles deliver drugs locally to inflamed sites of intestine, Biomaterials. 2018;185:322-32.
S. Bertoni, Z. Liu, A. Correia, J.P. Martins, A. Rahikkala, F. Fontana, M. Kemell, D. Liu, B. Albertini, N. Passerini*, W. Li* (co-corresponding author), H.A. Santos*. pH and reactive oxygen species-sequential responsive nano-in-micro composite for targeted therapy of inflammatory bowel disease, Advanced Functional Materials. 2018;28:1806175.
W. Li, Z. Liu, F. Fontana, Y. Ding, D. Liu, J. T. Hirvonen*, H. A. Santos*. Tailoring porous silicon for biomedical applications: from drug delivery to cancer immunotherapy. Advanced Materials. 2018;30:1703740.
Z. Liu†, Y. Li†, W. Li† (co-first author), C. Xiao, D. Liu, C. Dong, M. Zhang, E. Mäkilä, M. Kemell, J. Salonen, J. T. Hirvonen, H. Zhang*, D. Zhou*, X. Deng*, H. A. Santos*. Multifunctional nanohybrid based on porous silicon nanoparticles, gold nanoparticles and acetalated dextran for efficient liver regeneration and acute liver failure theranostics. Advanced Materials. 2018;30:1703393.
N. Kerdsakundee†, W. Li†,* (co-first author & co-corresponding author), J. P. Martins, Z. Liu, F. Zhang, M. Kemell, A. Correia, Y. Ding, M. Airavaara, J. T. Hirvonen, R. Wiwattanapatapee, H. A. Santos*. Multifunctional nanotube–mucoadhesive poly(methyl vinyl ether-co-maleic acid)@hydroxypropyl methylcellulose acetate succinate composite for site-specific oral drug delivery. Advanced Healthcare Materials. 2017;6:1700629.
W. Li, D. Liu, H. Zhang, A. Correia, E. Mäkilä, J. Salonen, J. T. Hirvonen, H. A. Santos*. Microfluidic assembly of a nano-in-micro dual drug delivery platform composed of halloysite nanotubes and a pH-responsive polymer for colon cancer therapy. Acta Biomaterialia. 2016;48:238-46.