Name of Research Group:

Epigenetic research group on reproduction and stem cell biology

Description of Research Group:

Our group is dedicated to investigations on epigenetic mechanisms in mammalian reproduction and stem cell biology.

Selected Publication (# co-corresponding author, * co-first author)
[1] Zhou, L.Q.#, Canagarajah, B., Zhao, Y.G., Baibakov, B., Maric, D., Dean, J.# (2017) BTBD18 licenses piRNA-generating loci through transcription elongation in mice. Dev Cell. 40, 453-466.
[2] Zhou, L.Q.#, Baibakov, B., Canagarajah, B., Xiong, B., and Dean, J.# (2017) Genetic mosaics and time-lapse imaging identify functions of H3.3 residues in oocyte-to-embryo transition. Development. 144, 519-528.
[3] Zhou, L.Q., Dean, J. (2015) Reprogramming the genome to totipotency in mouse embryos. Trends Cell Biol. 25, 82-91.
[4] Wu, J.*, Zhou, L.Q.*, Yu, W.*, Zhao, Z.G., Xie, X.M., Wang, W.T., Xiong, J., Li, M., Xue, Z., Wang, X., Zhang, P., Mao, BB., Hao, D.L., Lv, X., Liu, D.P. (2014). PML4 facilitates erythroid differentiation by enhancing the transcriptional activity of GATA-1. Blood. 123, 261-270.
[5] Zhou, L.Q.*, Wu, J.*, Wang, W.T., Yu, W., Zhao, G.N., Zhang, P., Xiong, J., Li, M., Xue, Z., Wang, X., Xie, X.M., Guo, Z.C., Lv, X., and Liu, D.P. (2012). The AT-rich DNA binding protein SATB2 promotes expression and physical association of human Ggamma- and Agamma-Globin genes. J Biol Chem. 287, 30641-30652.