教师个人主页
YANG MIN
Dehydroquinate synthase DHQS directly binds to streptomycin and regulates resistance of Mycobacterium bovis to streptomycin in a non-canonical mode.[J].Frontiers in Microbiology,2022,
1. Yang,M., Jia,S.-H., Tao,H.-L., Zhu,C., Jia,W.-Z., Hu,L.-H. and Gao,C.-H.* (2020) Cd(II)-binding transcriptional regulator interacts with isoniazid and regulates drug susceptibility in mycobacteria. J Biochem, 10.1093/jb/mvaa086. .
2. Yang M#, Zhang L#, Tao H-L#, Sun Y-C, Lou Z-Z, Jia W-Z, Hu L-H, Gao C-H*(2019) OxiR specifically responds to isoniazid and regulates isoniazid susceptibility in mycobacteria. FEMS Microbiol Lett. 366(10): fnz109. .
3. Gao C-H, Wei W-P, Tao H-L, Cai L-K, Jia W-Z, Hu L, Yang M*(2019). Cross-talk between the three furA orthologs in Mycobacterium smegmatis and the contribution to isoniazid resistance. J Biochem. 166(3): 237-243. .
4. Zhu C, Liu Y, Hu L-H, Yang M*, He Z-G*(2018) Molecular mechanism of the synergistic activity of ethambutol and isoniazid against Mycobacterium tuberculosis. J. Biol. Chem. 293(43): 16741-16750. .
5. Liu H, Yang M*, He Z-G* (2016) Novel TetR family transcriptional factor regulates expression of multiple transport-related genes and affects rifampicin resistance in Mycobacterium smegmatis. Sci Rep. 6: 27489. .
6. Zhao L1, Hu J1, Yang M* (2015) A GntR family transcription factor positively regulate mycobacterial isoniazid resistance by controlling the expression of a putative permease. BMC Microbiology. 15(214): PMC4609117. .
7. Yang M, Gao C, Cui T, An J & He Z-G* (2012) A TetR-like regulator broadly affects the expressions of diverse genes in Mycobacterium smegmatis. Nucleic Acids Res. 40(3): 1009–1020. .
8. Yang M, Gao C-H, Hu J, Lei Zhao, Huang Q, He Z-G*. InbR, a TetR family regulator, binds with isoniazid and influences multidrug resistance in Mycobacterium bovis BCG. Scientific Reports 2015, 5:13969. .
9. Yang M, Gao C-H, Hu J, Dong C & He Z-G* (2014) Characterization of the interaction between a SirR family transcriptional factor of Mycobacterium tuberculosis, encoded by Rv2788, and a pair of toxin-antitoxin proteins RelJ/K, encoded by Rv3357 and Rv3358. FEBS J. 281(12): 2726–2737. .
