Xiaotao Han

·Paper Publications

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Note:Magnetic targeting for enhancement of the activation efficiency of G protein coupled receptor with a two-pair coil system
Release time:2018-10-09  Hits:

Indexed by: Journal paper

Document Code: 10.1063/1.4939732

First Author: Quanliang Cao

Correspondence Author: Xiaotao Han

Journal: Review of Scientific Instruments

Included Journals: EI、SCI

Affiliation of Author(s): Wuhan National High Magnetic Field Center

Document Type: J

Volume: 87

Issue: 1

Page Number: 016103

Date of Publication: 2016-10-09

Abstract: Insufficient contact of drug with target cells is a primary reason for limited efficiency of G protein-coupled receptor activation. To overcome this limitation, a simple approach based on magnetic targeting for enhancing drug delivery towards the cell surfaces using magnetic nanoparticles and a two-pair coil system consisting of Helmholtz and Maxwell coils was reported.