·Scientific Research
Research Field
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Professor Liu Rong get her Ph.D in Tongji Medical College, HUST, majored in Pathophysiology. She is now an independent PI in Key Laboratory of Ministry of Education for Neurological Disorders, China; the outstanding scholar awarded by Hubei Natural Science Foundation; and members of several academic associations such as Chinese Association of Pathophysiology, Chinese Neuroscience Society and Hubei Society for Microcirculation. She is also the member of editorial board of several scientific journals such as Journal of Neurochemistry, Journal of Alzheimer Disease and Neuroscience Bulletin; the reviewer of more than twenty journals such as Science translational medicine, Cell reports, Theranostics, Journal of Neurochemistry, Hippocampus, Neuroscience Bulletin, etc; as well as the grant reviewer of National Natural Science Foundation of China and Medical Research Council of England.
With the research focused on the pathogenesis of Alzheimer’s disease and Depression, Professor Liu has published more than 50 papers with an H-index 25. As the main leader, she was granted more than 6 projects by National Natural Science Foundation of China. She has guided 8 PhD students and 6 graduated students to get their degree and obtain positions in universities and high-level hospitals. Five of her students wined the National Scholarship for Graduate Student.
More information can be found in:
Researchgate: https://www.researchgate.net/profile/Rong_Liu19
ORCID: https://orcid.org/0000-0001-7477-6520
Paper Publications
MORE+- [1] Hu W, Wang Z, Zhang H, Mahaman YAR, Huang F, Meng D, Zhou Y, Wang S, Jiang N, Xiong J, Westermarck J, Lu Y, Wang J, Wang X, Shentu Y, Liu R. Chk1 Inhibition Ameliorates Alzheimer's Disease Pathogenesis and Cognitive Dysfunction Through CIP2A/PP2A Signaling. Neurotherapeutics. 2022 Mar;19(2):570-591. doi: 10.1007/s13311-022-01204-z.
- [2] Meng D, Yang M, Hu L, Liu T, Zhang H, Sun X, Wang X, Chen Y*, Jin Y*, Liu R*. Rifaximin protects against circadian rhythm disruption-induced cognitive impairment through preventing gut barrier damage and neuroinflammation. J Neurochem. 2022 Oct 3. doi: 10.1111/jnc.15701.
- [3] Hu WT, Liuyang ZY, Tian Y, Liang JW, Zhang XL, Zhang HL, Wang G, Huo Y, Shentu YP, Wang JZ, Wang XC, Lu YM, Westermarck J, Man HY*, Liu R*. CIP2A deficiency promotes depression-like behaviors in mice through inhibition of dendritic arborization. EMBO Rep. 2022 Oct 28:e54911. doi:10.15252/embr.202254911.
- [4] Zhang H, Yang M, Wang X, Wei H, Du M, Wang M, Wang J, Chen Z, Peng C*, Liu R*. Zinc induces reactive astrogliosis through ERK dependent activation of Stat3 and promotes synaptic degeneration. J Neurochem. 2021 Dec;159(6):1016-1027.
- [5] Wei H, Zhang HL, Wang XC, Xie JZ, An DD, Wan L, Wang JZ, Zeng Y, Shu XJ, Westermarck J, Lu YM, Ohlmeyer M*, Liu R*. Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer's Disease Pathogenesis in Cell and Animal Models. Neurotherapeutics. 2020 Feb 24. doi: 10.1007/s13311-020-00841-6.
Patents
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Published Books
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Research Projects
MORE+- [1] 2006-2008国家自然科学基金 240,000 RMB 蛋白磷酸脂酶2A的酪氨酸磷酸化修饰在AD发病中的作用 项目负责人
- [2] 2013-2016 国家自然科学基金 700,000 RMB Tau-PP2A-Src 复合体对NMDA 受体的异常调控在阿尔茨海默病发生中的作用 项目负责人
- [3] 2015-2018 国家自然科学基金 700,000 RMB CIP2A对蛋白磷酸酯酶2A的调节及其在阿尔茨海默病发病中的作用 项目负责人
- [4] 2018-2021 国家自然科学基金 700,000 RMB CIP2A对星形胶质细胞活化调控及其突触损伤机制研究 项目负责人
- [5] 2020-2023国家自然科学基金 696,000 RMB DNA损伤导致细胞周期重入在神经退变中的作用及分子机制研究 项目负责人