Scientific Research
Research Interests: (1) Enzyme Expression and Utilization; (2) Rational Design of Enzyme
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[1] Fang Xingrong.Convolution Neural Network-Based Prediction of Protein Thermostability.Journal of Chemical Information and Modeling.2019,59(11):4833-4843
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[2] Guanlin Li.Identification of a hot-spot to enhance Candida rugosa lipase thermostability by rational design methods.RSC Advances.2018,8:1948-1957
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[3] Li Xu.Surface-Displayed Thermostable Candida Rugosa Lipase 1 for Docosahexaenoic Acid Enrichment.Appl Biochem Biotechnol..2019,190(1):218-231
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[4] Pan Xiaoxin.Efficient display of active Geotrichum sp. lipase on Pichia pastoris cell wall and its application as a whole-cell biocatalyst to enrich EPA and DHA in fish oil.Journal of Agricultural and Food Chemistry.2012,60(38):9673-9679
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[5] Xu Li.Overexpression of Candida rugosa lipase lip1 via combined strategies in Pichia pastoris.Enzyme and Microbial Technology.2015,82:115-124
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[1] 高效拆分2-芳基丙酸类手性药物的皱褶假丝酵母嵌合脂肪酶的研究, National Natural Science Foundation of China (NSFC), 2012-01-01-2015-12-01
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[2] De novo design of highly active lipases via backbone assembly, National Natural Science Foundation of China (NSFC), 2020-01-01-2023-12-01
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[3] 基于骨架组装从头设计活性脂肪酶, National Natural Science Foundation of China (NSFC), 2020-01-01-2023-12-01
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[4] Study on chimeric lipases from Candida rugosa for the enantioselective resolution of 2-arylpropionic acid, National Natural Science Foundation of China (NSFC), 2012-01-01-2015-12-01
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[5] 饲料用海洋脂肪酶--单细胞蛋白联产关键技术及产品, The 863 Program, 2014-01-01-2016-12-01