张胜民

个人信息

教授 博士生导师 硕士生导师

性别:男

在职信息:在职

所在单位:生命科学与技术学院

学历:研究生(博士)毕业

学位:工学博士学位

毕业院校:武汉理工大学

学科:生物医学工程

曾获荣誉:
2021    President-Elect, TERMIS-AP
2016    IUSBSE Fellow, FBSE

学术荣誉:
2014    讲座教授
2018    “973计划”项目及项目首席科学家

个人简介

张胜民:博士、二级教授/博士生导师、国际生物材料科学与工程院Fellow (FBSE)、TERMIS亚太当选主席、中国生物材料学会副理事长、国家重点研发计划首席科学家、中国科协首席科学传播专家;华中科技大学医疗器械监管科学研究院院长、华中科技大学先进生物材料与组织工程交叉学科中心主任、国际再生医学材料联合实验室主任。兼任CFDA/NMPA医疗器械技术审评专家咨询委员会委员、CFDA医疗器械分类技术委员会委员。美国Rice University久负盛名讲座Advances in Tissue  Engineering客座教授,Advanced Healthcare Materials、Tissue Engineering、Biomedical Materials等期刊编委和特邀主编。


张胜民教授在先进再生医学材料、生物3D打印专用生物材料、细胞能量生物材料、多分子模板仿生矿化、功能元素摻杂钙磷生物材料等领域做出了系统性、开创性贡献。是国际再生医学材料系列大会、全国再生医学材料系列大会两大学术交流平台的创始人和联合主席、国际组织工程系列大会共同主席。主持承担国家重点研发计划、国家自然科学基金重点项目、国家自然科学基金国际合作重点项目、国家863计划项目、国家科技支撑计划项目、国家重大研究计划项目、科技部政府间国际科技合作计划项目等30余项, 获得中国和美国发明专利授权30余项,部分重大发明获得转化,取得中国CFDA/NMPA和美国FDA医疗器械产品注册证5项,产生显著社会经济效益。 在Science Advances,Chemical Reviews,ACS Nano、Biomaterials,Biotechnology Advances等权威期刊发表学术论文100余篇。张胜民教授因其“在再生医学材料研发、 临床转化和促进生物材料科学公共进步领域所作出的公认的杰出贡献”,而被授予国际生物材料科学与工程学会联合会会士(IUSBSE Fellow, FBSE)终身荣誉称号。


近年代表性论文(2014-2020)


  1. Haoming Liu, Yingying Du, Jean-Philippe St-Pierre, Mads S. Bergholt, Hélène Autefage, Jianglin Wang, Mingle Cai, Gaojie Yang, Molly M.      Stevens*, Shengmin Zhang*. Bioenergetic-active materials enhance tissue regeneration by modulating cellular metabolic state. Science        Advances 2020, 6, eaay7608 (A Cover Highlight)

  2. Matthew. L. Bedell, Adam. M. Navara, Yingying Du, Shengmin Zhang*, and Antonios G. Mikos*. Polymeric systems for bioprinting. Chemical Reviews, 2020, 120, 10744−10792. A Cover Highlight

  3. Xiao Li, Yifan Wang, Yan Chen, Pan Zhou, Kang Wei, Huan Wang, Jianglin Wang, Huang Fang*, Shengmin Zhang*. Hierarchically constructed selenium-doped bone-mimetic nanoparticles promote ROS-mediated autophagy and apoptosis for bone tumor inhibition, Biomaterials 2020,  257, 120253

  4. Gaojie Yang, Haoming Liu, Yi Cui, Jiaqi Li Xuan Zhou, Nuoxin Wang, Feige Wu, Yan LiYu Liu, Xingyu Jiang*, Shengmin Zhang*. Bioinspired membrane provides periosteum-mimetic microenvironment for accelerating vascularized bone regeneration, Biomaterials 2021, 268, 120561

  5. Yao Zha, Tianyi Lin, Yawu Li, Xin Zhang, Zihao Wang, Zubing Li, Yongqin Ye, Bin Wang*, Shengmin Zhang*, Jianglin Wang*. Exosome-mimetics  as an engineered gene-activated matrix induces in-situ vascularized osteogenesis. Biomaterials, 2020, 247, 119985

  6. Zihao Wang, Chungeng Liu, Di Zhu, Xiang Gu, Yin Xu, Qinghua Qin, Nianguo Dong, Shengmin Zhang*, Jianglin Wang*. Untangling the co-effects of oriented nanotopography and sustained anticoagulation in a biomimetic intima on neovessel remodeling. Biomaterials, 231,119654, 2020.

  7. Haoming Liu, Yingying Du, Gaojie Yang, Xixi Hu, Lin Wang, Bin Liu, Jianglin Wang, and Shengmin Zhang*. Delivering proangiogenic factors from 3D-printed polycaprolactone scaffolds for vascularized bone regeneration. Advanced Healthcare Materials 2020, 2000727. A Cover Highlight

  8. Weikang Hu, Zijian Wang, Yao Zha, Xiang Gu, Wenjie You, Yu Xiao, Xinghuan Wang*, Shengmin Zhang*, and Jianglin Wang*, High flexible and broad antibacterial nanodressing induces complete skin repair with angiogenic and follicle regeneration. Advanced Healthcare Materials, 2020, 2000035.

  9. Yingying Du, Jason L. Guo, Jianglin Wang, Antonios G. Mikos*, Shengmin Zhang*. Hierarchically designed bone scaffolds: from internal cues to external stimuli. Biomaterials, 2019, 218, 119334

  10. Shenglong Tan, Shangsi Chen, Yifan Wang a,b, Feige Wu, Yufei Shi, Jianglin Wang, Yingying Du, Shengmin ZhangEnhanced effect of       nano-monetite hydrosol on dentin remineralization and tubule occlusion, Dental Materials, 2020, https://doi.org/10.1016/j.dental.2020.03.028

  11. Yan Li, Hang Hao, Zhengyu Zhong, Mengdie Li, Jiaqi Li, Yingying Du, Xiaodan Wu, Jianglin Wang, and Shengmin Zhang*. Assembly mechanism of high-crystallized selenium-doped hydroxyapatite nanorods via particle attachment and their effect on stem cells fate. ACS Biomaterials Science and Engineering, 2019, 5, 12, 6703-6714

  12. Yingying Du, Haoming Liu, Qin Yang, Shuai Wang, Jianglin Wang, Jun Ma, Insup Noh, Antonios G. Mikos*, Shengmin Zhang*. Selective laser  sintering scaffold with hierarchical architecture and gradient composition for osteochondral repair in rabbits. Biomaterials, 2017, 137: 37-48

  13.  Gaojie Yang, Haoming Liu,Xixi Hu,Zetao Chen,Thor E. Friis,Jianglin Wang,Yin Xiao* and Shengmin Zhang*. Bio-inspired hybrid nanoparticles    promote vascularized bone regeneration in a morphology-dependent manner. Nanoscale, 2017, 9: 5794-5805 A Cover Highlight

  14. Yifan Wang, Jianglin Wang, Hang Hao, Mingle Cai, Shiyao Wang, Jun Ma, Yan Li, Chuanbin Mao,* and Shengmin Zhang*.  In vitro and in vivo  mechanism of bone tumor inhibition by selenium-doped bone mineral nanoparticles. ACS Nano, 2016, 10: 9927-9937

  15. Jianglin Wang, Gaojie Yang, Yifan Wang, Yinying Du, Haoming Liu,Ye Zhu, Chuanbin Mao,* and Shengmin Zhang*. Chimeric protein template-induced shape control of bone mineral nanoparticles and its impact on mesenchymal stem cell fate. Biomacromolecules, 2015, 16: 1987-1996

  16. Yanhua Wang, Hang Hao, Haoming Liu, Yifan Wang, Yan Li, Gaojie Yang, Jun Ma, Chuanbin Mao,* and Shengmin Zhang*. Selenite-releasing  bone mineral nanoparticles retard bone tumor growth and improve healthy tissue functions in vivo. Advanced Healthcare Materials, 2015, 4: 1813-1818  A Cover Highlight 

  17. Jun Ma, Jianglin Wang, Xin Ai, Shengmin Zhang*. Biomimetic self-assembly of apatite hybrid materials: From a single molecular template to bi-/multi-molecular templates. Biotechnology Advances, 2014, 32:744–760


Guest-edited Special Issue:

Shengmin Zhang and Antonios G. Mikos. Biomaterials for Regenerative Medicine. Advanced Healthcare Materials, Vol 9, No 23, 2020. WILEY-VCH. Germany.


主要科研项目(PI: Shengmin Zhang)


2018-2021        National Key R & D Project “Biomaterials and Controlled Release System  for Accelerated Tissue Regeneration”

2019-2022        National Science Foundation of China (NSFC) “3D Printing Bio-energy       Active Materials for Bone Regeneration”

2016-2021        Key Projects from Ministry of Education of China and Ministry of Finance of China: “Key Innovative Team for Interdisciplinary Advancement on                                      Biomaterials and Regenerative Medicine”

2016-2019        NSFC Key Project: “Influence and Its Regulation of 3-D Micro-Pattern         Structure of Biomaterials on MSCs Differentiation”

2016-2017        NSFC Key Project for International Cooperation: “Biomimetic gradient       regenerative medical materials for repairing complex defects of  cartilage and bone”

2016-2019        NSFC: “Study on Fabrication of Bioenergic Materials Based on ATP-Pathway and its Molecular Mechanism of Promoting Bone Repair”

2012-2016        National Key Project for Science and Technology Development “Innovative Biomaterials Devices for Bone and Spine Repair and Regeneration”

2012-2016        National Key Basic Science Project: “Controlled Preparation of Micro/Nano-Multi-scale Structural Biomaterials for Accelerated Bone Regeneration”

2011-2013        International Cooperative Program of Ministry of Science and Technology of China: “Surface Coating of PEEK with Functional Element Doped Hydroxyapatite and its Application”

2011-2013        NSFC: “Molecular Mechanism Discovery of Bone Healing Triggered by Ca-P Bone Substitutes Containing Elements Si and Zn”

2009-2011        NSFC: “A New Fabrication for Biominerization Nano-Bone Materials Based on Composite Template Co-assembly and Their Mechanism”

2006-2010        National “863” High-Tech Program: “Novel Controlled Degradable Biomaterials Composed of Inorganic and Organic Composition for Repairing of Bone and Cartilage defects”




团队成员