个人信息
性别:男
在职信息:在职
所在单位:生命科学与技术学院
学历:研究生(博士)毕业
学位:工学博士学位
毕业院校:武汉理工大学
学科:生物医学工程曾获荣誉:
2021 President-Elect, TERMIS-AP
2016 IUSBSE Fellow, FBSE
个人简介
张胜民:博士、二级教授/博士生导师、国际生物材料科学与工程院Fellow (FBSE)、TERMIS亚太当选主席、中国生物材料学会副理事长、国家重点研发计划首席科学家、中国科协首席科学传播专家;华中科技大学医疗器械监管科学研究院院长、华中科技大学先进生物材料与组织工程交叉学科中心主任、国际再生医学材料联合实验室主任。兼任CFDA/NMPA医疗器械技术审评专家咨询委员会委员、CFDA医疗器械分类技术委员会委员。美国Rice University久负盛名讲座Advances in Tissue Engineering客座教授,Advanced Healthcare Materials、Tissue Engineering、Biomedical Materials等期刊编委和特邀主编。
张胜民教授在先进再生医学材料、生物3D打印专用生物材料、细胞能量生物材料、多分子模板仿生矿化、功能元素摻杂钙磷生物材料等领域做出了系统性、开创性贡献。是国际再生医学材料系列大会、全国再生医学材料系列大会两大学术交流平台的创始人和联合主席、国际组织工程系列大会共同主席。主持承担国家重点研发计划、国家自然科学基金重点项目、国家自然科学基金国际合作重点项目、国家863计划项目、国家科技支撑计划项目、国家重大研究计划项目、科技部政府间国际科技合作计划项目等30余项, 获得中国和美国发明专利授权30余项,部分重大发明获得转化,取得中国CFDA/NMPA和美国FDA医疗器械产品注册证5项,产生显著社会经济效益。 在Science Advances,Chemical Reviews,ACS Nano、Biomaterials,Biotechnology Advances等权威期刊发表学术论文100余篇。张胜民教授因其“在再生医学材料研发、 临床转化和促进生物材料科学公共进步领域所作出的公认的杰出贡献”,而被授予国际生物材料科学与工程学会联合会会士(IUSBSE Fellow, FBSE)终身荣誉称号。
近年代表性论文(2014-2020)
Haoming Liu, Yingying Du, Jean-Philippe St-Pierre, Mads S. Bergholt, Hélène Autefage, Jianglin Wang, Mingle Cai, Gaojie Yang, Molly M. Stevens*, Shengmin Zhang*. Bioenergetic-active materials enhance tissue regeneration by modulating cellular metabolic state. Science Advances 2020, 6, eaay7608 (A Cover Highlight)
Matthew. L. Bedell, Adam. M. Navara, Yingying Du, Shengmin Zhang*, and Antonios G. Mikos*. Polymeric systems for bioprinting. Chemical Reviews, 2020, 120, 10744−10792. (A Cover Highlight)
Xiao Li, Yifan Wang, Yan Chen, Pan Zhou, Kang Wei, Huan Wang, Jianglin Wang, Huang Fang*, Shengmin Zhang*. Hierarchically constructed selenium-doped bone-mimetic nanoparticles promote ROS-mediated autophagy and apoptosis for bone tumor inhibition, Biomaterials 2020, 257, 120253
Gaojie Yang, Haoming Liu, Yi Cui, Jiaqi Li, Xuan Zhou, Nuoxin Wang, Feige Wu, Yan Li,Yu Liu, Xingyu Jiang*, Shengmin Zhang*. Bioinspired membrane provides periosteum-mimetic microenvironment for accelerating vascularized bone regeneration, Biomaterials 2021, 268, 120561
Yao Zha, Tianyi Lin, Yawu Li, Xin Zhang, Zihao Wang, Zubing Li, Yongqin Ye, Bin Wang*, Shengmin Zhang*, Jianglin Wang*. Exosome-mimetics as an engineered gene-activated matrix induces in-situ vascularized osteogenesis. Biomaterials, 2020, 247, 119985
Zihao Wang, Chungeng Liu, Di Zhu, Xiang Gu, Yin Xu, Qinghua Qin, Nianguo Dong, Shengmin Zhang*, Jianglin Wang*. Untangling the co-effects of oriented nanotopography and sustained anticoagulation in a biomimetic intima on neovessel remodeling. Biomaterials, 231,119654, 2020.
Haoming Liu, Yingying Du, Gaojie Yang, Xixi Hu, Lin Wang, Bin Liu, Jianglin Wang, and Shengmin Zhang*. Delivering proangiogenic factors from 3D-printed polycaprolactone scaffolds for vascularized bone regeneration. Advanced Healthcare Materials 2020, 2000727. (A Cover Highlight)
Weikang Hu, Zijian Wang, Yao Zha, Xiang Gu, Wenjie You, Yu Xiao, Xinghuan Wang*, Shengmin Zhang*, and Jianglin Wang*, High flexible and broad antibacterial nanodressing induces complete skin repair with angiogenic and follicle regeneration. Advanced Healthcare Materials, 2020, 2000035.
Yingying Du, Jason L. Guo, Jianglin Wang, Antonios G. Mikos*, Shengmin Zhang*. Hierarchically designed bone scaffolds: from internal cues to external stimuli. Biomaterials, 2019, 218, 119334
Shenglong Tan, Shangsi Chen, Yifan Wang a,b, Feige Wu, Yufei Shi, Jianglin Wang, Yingying Du, Shengmin Zhang∗,Enhanced effect of nano-monetite hydrosol on dentin remineralization and tubule occlusion, Dental Materials, 2020, https://doi.org/10.1016/j.dental.2020.03.028
Yan Li, Hang Hao, Zhengyu Zhong, Mengdie Li, Jiaqi Li, Yingying Du, Xiaodan Wu, Jianglin Wang, and Shengmin Zhang*. Assembly mechanism of high-crystallized selenium-doped hydroxyapatite nanorods via particle attachment and their effect on stem cells fate. ACS Biomaterials Science and Engineering, 2019, 5, 12, 6703-6714
Yingying Du, Haoming Liu, Qin Yang, Shuai Wang, Jianglin Wang, Jun Ma, Insup Noh, Antonios G. Mikos*, Shengmin Zhang*. Selective laser sintering scaffold with hierarchical architecture and gradient composition for osteochondral repair in rabbits. Biomaterials, 2017, 137: 37-48
Gaojie Yang, Haoming Liu,Xixi Hu,Zetao Chen,Thor E. Friis,Jianglin Wang,Yin Xiao* and Shengmin Zhang*. Bio-inspired hybrid nanoparticles promote vascularized bone regeneration in a morphology-dependent manner. Nanoscale, 2017, 9: 5794-5805 (A Cover Highlight)
Yifan Wang, Jianglin Wang, Hang Hao, Mingle Cai, Shiyao Wang, Jun Ma, Yan Li, Chuanbin Mao,* and Shengmin Zhang*. In vitro and in vivo mechanism of bone tumor inhibition by selenium-doped bone mineral nanoparticles. ACS Nano, 2016, 10: 9927-9937
Jianglin Wang, Gaojie Yang, Yifan Wang, Yinying Du, Haoming Liu,Ye Zhu, Chuanbin Mao,* and Shengmin Zhang*. Chimeric protein template-induced shape control of bone mineral nanoparticles and its impact on mesenchymal stem cell fate. Biomacromolecules, 2015, 16: 1987-1996
Yanhua Wang, Hang Hao, Haoming Liu, Yifan Wang, Yan Li, Gaojie Yang, Jun Ma, Chuanbin Mao,* and Shengmin Zhang*. Selenite-releasing bone mineral nanoparticles retard bone tumor growth and improve healthy tissue functions in vivo. Advanced Healthcare Materials, 2015, 4: 1813-1818 (A Cover Highlight)
Jun Ma, Jianglin Wang, Xin Ai, Shengmin Zhang*. Biomimetic self-assembly of apatite hybrid materials: From a single molecular template to bi-/multi-molecular templates. Biotechnology Advances, 2014, 32:744–760
Guest-edited Special Issue:
Shengmin Zhang and Antonios G. Mikos. Biomaterials for Regenerative Medicine. Advanced Healthcare Materials, Vol 9, No 23, 2020. WILEY-VCH. Germany.
主要科研项目(PI: Shengmin Zhang)
2018-2021 National Key R & D Project “Biomaterials and Controlled Release System for Accelerated Tissue Regeneration”
2019-2022 National Science Foundation of China (NSFC) “3D Printing Bio-energy Active Materials for Bone Regeneration”
2016-2021 Key Projects from Ministry of Education of China and Ministry of Finance of China: “Key Innovative Team for Interdisciplinary Advancement on Biomaterials and Regenerative Medicine”
2016-2019 NSFC Key Project: “Influence and Its Regulation of 3-D Micro-Pattern Structure of Biomaterials on MSCs Differentiation”
2016-2017 NSFC Key Project for International Cooperation: “Biomimetic gradient regenerative medical materials for repairing complex defects of cartilage and bone”
2016-2019 NSFC: “Study on Fabrication of Bioenergic Materials Based on ATP-Pathway and its Molecular Mechanism of Promoting Bone Repair”
2012-2016 National Key Project for Science and Technology Development “Innovative Biomaterials Devices for Bone and Spine Repair and Regeneration”
2012-2016 National Key Basic Science Project: “Controlled Preparation of Micro/Nano-Multi-scale Structural Biomaterials for Accelerated Bone Regeneration”
2011-2013 International Cooperative Program of Ministry of Science and Technology of China: “Surface Coating of PEEK with Functional Element Doped Hydroxyapatite and its Application”
2011-2013 NSFC: “Molecular Mechanism Discovery of Bone Healing Triggered by Ca-P Bone Substitutes Containing Elements Si and Zn”
2009-2011 NSFC: “A New Fabrication for Biominerization Nano-Bone Materials Based on Composite Template Co-assembly and Their Mechanism”
2006-2010 National “863” High-Tech Program: “Novel Controlled Degradable Biomaterials Composed of Inorganic and Organic Composition for Repairing of Bone and Cartilage defects”