华中科技大学主页平台管理系统 CHEN JUN WEI--英文主页--Scientific Research

CHEN JUN WEI 研究员（自然科学）

Research fields: Cell mechanics, mechanomedicine, stem cell mechanobiology and tumor mechanobiology.Published 12 SCI papers in journals such as Science Advances, Nature Communications, Nature Materials, Nature Protocols and Cell Research. Has holds 6 patents for anti-cancer drugs. Our researches are mainly engaged in regulating fate of tumor and embryonic stem cell by mechanical signals, mainly...Detials

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Scientific Research Current position: 英文主页 > Scientific Research

Research Field

Cell mechanics, mechanomedicine, stem cell mechanobiology and tumor mechanobiology.

Paper Publications MORE+

Sun J$, Chen JW$, Mohagheghian E, Wang N*. Force induced gene upregulation does not follow the weak power law but depends on H3K9 demethylation. Science advances，6, 14, eaay9095,2020. $Co-first authors. *Corresponding senior author.
Chen JW$, Cao X$, An Q, Zhang Y, Li K, Yao W, Shi F, Pan Y, Jia Q, Zhou W, Yang F, Wei F, Wang N*, Yu B*. Inhibition of cancer stem cell like cells by a synthetic retinoid. Nature Communications Apr 11; 9 (1):1406, 2018. $Co-first authors. *Co-Corresponding author
Tan Y$, Tajik A$, Chen JW$, Jia Q, Chowdhury F, Wang L, Junjian Chen JJ, Zhang S, Ying Hong Y, Yi H, Wu DC, Zhang Y, Wei F, Poh YC, Seong J, Singh R, Lin LJ, Doğanay S, Li Y, Jia H, Ha T, Wang Y, Huang B, Wang N*. Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression. Nature Communications. 5: 4619, 2014. $Co-first authors.*Corresponding senior author.
J Chen, N Wang. Tissue cell differentiation and multicellular evolution via cytoskeletal stiffening in mechanically stressed microenvironments. Acta Mechanica Sinica, 2018
Mohagheghian E, Luo J, Chen JW, Chaudhary G, Chen J, Sun J, Ewoldt RH, Wang N*. Quantifying compressive forces between living cell layers and within tissues using elastic round microgels. Nature Communications. May 14; 9(1):1878, 2018.

Patents

Retinoid compound, preparation method therefor, intermediates thereof and application thereof

Published Books

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Research Projects

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