3D Interfacing between Soft Electronic Tools and Complex Biological Tissues
发布时间：2024-06-03
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- 论文类型：
- 期刊论文
- 第一作者：
- Hegeng Li
- 通讯作者：
- YongAn Huang,Lizhi Xu
- 合写作者：
- Hongzhen Liu,Mingze Sun
- 发表刊物：
- Advanced Materials
- 收录刊物：
- SCI
- 项目来源：
- Research Grants Council, University Grants Committee (Grant Nos. 27210019 and 17200320) , etc.
- 卷号：
- 33
- 期号：
- 3
- DOI码：
- 10.1002/adma.202004425
- 发表时间：
- 2020-12-06
- 摘要：
- Recent developments in soft functional materials have created opportunities for building bioelectronic devices with tissue-like mechanical properties. Their integration with the human body could enable advanced sensing and stimulation for medical diagnosis and therapies. However, most of the available soft electronics are constructed as planar sheets, which are difficult to interface with the target organs and tissues that have complex 3D structures. Here, the recent approaches are highlighted to building 3D interfaces between soft electronic tools and complex biological organs and tissues. Examples involve mesh devices for conformal contact, imaging-guided fabrication of organ-specific electronics, miniaturized probes for neurointerfaces, instrumented scaffold for tissue engineering, and many other soft 3D systems. They represent diverse routes for reconciling the interfacial mismatches between electronic tools and biological tissues. The remaining challenges include device scaling to approach the complexity of target organs, biological data acquisition and processing, 3D manufacturing techniques, etc., providing a range of opportunities for scientific research and technological innovation.