Li Minghao
Today, we have all become increasingly aware that the practice of organic chemistry is having a major detrimental impact on the environment. Given the plethora of synthetic methods at our disposal, the challenges for organic synthesis go beyond one of molecular complexity to encompass more convergent, atom/step efficient and sustainable processes. In recognition of the inevitable switch that must take place, we continue to devote most of our research program to developing alternative technologies that address the three key parameters associated with research today in organic synthesis:
(i) Solvents: Harness Non-covalent Interaction for Replacement of Harmful Solvent;
(ii) Starting Materials: Valorize Bio-derived Platform Molecules into Heterocycles;
(iii) Process: Design Tandem Catalysis.
Luxia Guo, Meng Ye, Luigi Vaccaro, Minghao Li,* and Yanlong Gu*, Two‐Step Access to β ‐Substituted o ‐Hydroxyphenyl Ethyl Ketones from 4‐Chromanone and its Application in Preparation of a Silica‐Supported Cobalt(II) Salen Complex, Advanced Synthesis and Catalysis, 2021, 363, 4754 – 4760.
Shaomin Chen, Minghao Li * and Yanlong Gu*, Acid-catalyzed cleavage of C–C bonds enables atropaldehyde acetals as masked C2 electrophiles for organic synthesis, Chemical Communications, 2021, 57, 10431.
Feng Gao, Rongxian Bai, Minghao Li * and Yanlong Gu*, Dipolar HCP materials as alternatives to DMF solvent for azide-based synthesis, Green Chemistry, 2021, 23, 7499-7505.
Luxia, Guo; Zihao, Chen; Hongmei, Zhu, Minghao Li,* Yanlong Gu,* Acid-catalyzed chemodivergent reactions of 2, 2-dimethoxyacetaldehyde and anilines, Chinese Chemical Letters, 2021, 32, 1419–1422.
Shaomin Chen, Rongxian Bai, Minghao Li,* Ping Liu, Yanlong Gu,* Acid‐Acid‐Catalyzed Tandem Reactions Driven by an Additive‐like Component, The Chemical Record, 2021, 21, 87–115.
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