华中科技大学生命科学与技术学院教授、原院长、人类基因组中心主任；教育部长江学者，首批国家级高层次人才，美国科学促进会(AAAS)会士。长期聚焦罕见遗传病和重大心血管与神经系统疾病，采用遗传学、基因组学、蛋白质组学、3D基因组学、iPS分化与类器官模型、疾病动物模型、蛋白质冷冻电镜结构生物学、基因编辑和基因治疗等技术手段，探索疾病遗传学结构与分子病理机制，发现精准诊疗新靶点，开发新的干预与治疗技术。 已发表2...
美国克立夫兰州立大学 Business Administration Postgraduate (Master's Degree)
美国康奈尔大学 Genetics Postgraduate (Doctoral)
甘肃农业大学 Undergraduate (Bachelor’s degree)
疾病基因组学、分子机制、靶向治疗
Angiogenic factor AGGF1 blocks neointimal formation after vascular injury via interaction with integrin α7 on vascular smooth muscle cells
Hyperlipidemia patients carrying LDLR splicing mutation c.1187-2A>G respond favorably to rosuvastatin and PCSK9 inhibitor evolocumab
Identification and characterization of a special type of subnuclear structure: AGGF1-coated paraspeckles.
Genome-Wide Association Study for Idiopathic Ventricular Tachyarrhythmias Identifies Key Role of CCR7 and PKN2 in Calcium Homeostasis and Cardiac Rhythm Maintenance
Endothelial Cell Metabolic Memory Causes Cardiovascular Dysfunction In Diabetes
Identification and Functional Analysis of Two New De Novo KCNMA1 Variants Associated with Liang-Wang syndrome
