Indexed by: Journal paper

Journal: Chemical Engineering Journal

Included Journals: SCI

Affiliation of Author(s): 华中科技大学

Place of Publication: 瑞士

Discipline: 物理学

Funded by: 国基金

Document Type: J

Volume: 499

Page Number: 1-9

ISSN No.: 1385-8947

Key Words: Wearable Surface enhanced Raman scattering In-situ detection Metabolite VOCs gas

Date of Publication: 2024-09-20

Impact Factor: 13.4

Teaching and Research Group: 武汉光电国家研究中心

Abstract: Diagnosis of diseases by monitoring the metabolite concentration on the skin surface and volatile organic compounds (VOCs) in exhaled gas is an active area of research with great potential for development and application. Therefore, the development of a sensor that can monitor in real time slight changes in metabolite concentrations on the surface of the skin in the resting state and accurately detect VOCs gases in exhaled gas is of significant practical value. To address these challenges, we designed and fabricated the wearable Bionic Sea urchin-Cavity (BSC) SERS sensor with high sensitivity and adaptability. Our testing revealed that the SERS sensor exhibited strong responsiveness to human metabolites. The subtle concentration changes in urea on the resting state skin surface also successfully detected. Furthermore, the SERS sensor successfully detected trace acetone gas volatilized from the 30 mmol/L aqueous acetone solution similar to the acetone concentration in diabetic blood. We anticipate that this SERS sensor could serve as a multi-functional wearable device for medical applications and provide a new platform for the field.